Spectrin beta Chain, Erythrocyte (SPTB) anticorps

N° du produit ABIN1109122

Cet anticorps Souris Monoclonal détecte spécifiquement Spectrin beta Chain, Erythrocyte dans WB, IF et IP. Il présente une réactivité envers Humain.

Aperçu rapide pour Spectrin beta Chain, Erythrocyte (SPTB) anticorps (ABIN1109122)

Antigène: Spectrin beta Chain, Erythrocyte (SPTB)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: DB2

Détail du produit

Specificité: The antibody clone AF10 is specific to the 240 kDa Erythroid alpha-Spectrin. This antibody is suitable for Various immunochemical reactions to detect Erythroid Spectrins, Identification of Erythroid leukemias (Ref.1).

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Purified

Immunogène: Ghost proteins of Human red blood cells. Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, 0.09 % Sodium Azide, 1.0 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détail du antigène

Antigène: Spectrin beta Chain, Erythrocyte (SPTB)

Autre désignation: Spectrin beta Chain (Erythrocyte) / SPTB

Sujet: Erythroid spectrins, some other proteins of erythroid cytoskeleton, and the transmembrane protein band 3 are highly specific for erythrocytes and their progenitors. They are more reliable markers for erythroid differentiation than Glycophorin A, the commonly used marker for erythroid differentiation, because Glycophorin A is expressed also in many cell lines otherwise exhibiting mainly megakaryotic charasteristics.Synonyms: Beta-I spectrin, SPTB1

ID gène: 6710

NCBI Accession: NP_000338

UniProt: P11277

Pathways: Regulation of Actin Filament Polymerization