anticorps RGD1564516, anticorps MGC99322, anticorps TIMD4, anticorps B430010N18Rik, anticorps TIM-4, anticorps Tim4, anticorps SMUCKLER, anticorps TIM4, anticorps T-cell immunoglobulin and mucin domain containing 4, anticorps T-cell immunoglobulin and mucin domain containing 4 L homeolog, anticorps T cell immunoglobulin and mucin domain containing 4, anticorps Timd4, anticorps TIMD4, anticorps timd4.L
Sujet
TIMD-4 is a type I transmembrane protein belonging to the immunoglobulin superfamily, containing one Ig-like V-type (immunoglobulin-like) domain. TIMD-4 is expressed in Mac1+ cells in spleen, lymph nodes and fetal liver. TIMD-4 binds apoptotic cells by recognizing phosphatidylserine via its immunoglobulin domain. TIMD-4 in fibroblasts enhanced their ability to engulf apoptotic cells. TIMD-4 is involved in regulating T-cell proliferation and lymphotoxin signaling. TIMD-4 and TIMD-1 are phosphatidylserine receptors for the engulfment of apoptotic cells, and are also involved in intracellular signaling in which exosomes are involved.Synonyms: T-cell immunoglobulin and mucin domain-containing protein 4, T-cell membrane protein 4, TIM-4, TIM4, TIMD-4