TIMD4 anticorps

N° du produit ABIN1109254

Cet anticorps Hamster Monoclonal détecte spécifiquement TIMD4 dans IF, EIA et Func. Il présente une réactivité avec des échantillons de Souris.

Aperçu rapide pour TIMD4 anticorps (ABIN1109254)

Antigène: TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Reactivité: Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp TIMD4 est non-conjugé

Application: Immunofluorescence (IF), Enzyme Immunoassay (EIA), Functional Studies (Func)

Clone: Kat5-18

Détail du produit anti-TIMD4 anticorps

Specificité: The monoclonal antibody Kat5-18 recognizes T-cell immunoglobulin and mucin domain containing molecule (TIMD-4, also called TIM-4).

Réactivité croisée (Details): Species reactivity (tested):Mouse

Purification: Purified

Immunogène: Mouse peritoneal cells

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % bovine serum albumin

Stock: 4 °C

Stockage commentaire: Store at 2 - 8 °C.

Détails sur TIMD4

Antigène: TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Autre désignation: TIMD4

Sujet: TIMD-4 is a type I transmembrane protein belonging to the immunoglobulin superfamily, containing one Ig-like V-type (immunoglobulin-like) domain. TIMD-4 is expressed in Mac1+ cells in spleen, lymph nodes and fetal liver. TIMD-4 binds apoptotic cells by recognizing phosphatidylserine via its immunoglobulin domain. TIMD-4 in fibroblasts enhanced their ability to engulf apoptotic cells. TIMD-4 is involved in regulating T-cell proliferation and lymphotoxin signaling. TIMD-4 and TIMD-1 are phosphatidylserine receptors for the engulfment of apoptotic cells, and are also involved in intracellular signaling in which exosomes are involved.Synonyms: T-cell immunoglobulin and mucin domain-containing protein 4, T-cell membrane protein 4, TIM-4, TIM4, TIMD-4

ID gène: 276891

NCBI Accession: NP_848874

UniProt: Q6U7R4

Pathways: Cancer Immune Checkpoints