Transglutaminase 2 anticorps

N° du produit ABIN1109303

Il existe 1 publication pour ce produit. L’anticorps anti-Transglutaminase 2 Monoclonal Souris est utilisé pour la détection de Transglutaminase 2 dans des échantillons de Humain et Cobaye. Il a été validé pour WB, IHC (fro) et EIA.

Aperçu rapide pour Transglutaminase 2 anticorps (ABIN1109303)

Antigène: Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

Reactivité: Humain, Cobaye

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Transglutaminase 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone: 7D2

Détail du produit anti-Transglutaminase 2 anticorps

Réactivité croisée (Details): Species reactivity (tested):Human, Guinea Pig.

Purification: Affinity Chromatography on Protein A

Isotype: IgG3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in distilled water.

Buffer: 0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None

Références pour anticorps anti-Transglutaminase 2 (ABIN1109303)

Maffei, Laverrière, Wu, Triboulet, Perrinet, Duchateau, Matondo, Hollis, Gourley, Rupp, Keillor, Subtil: "Infection-driven activation of transglutaminase 2 boosts glucose uptake and hexosamine biosynthesis in epithelial cells." dans: The EMBO journal, Vol. 39, Issue 8, pp. e102166, (2020) (PubMed).

Détails sur Transglutaminase 2

Antigène: Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

Autre désignation: Transglutaminase-2

Sujet: Transglutaminase II catalyzes calcium-dependent post-translational modification of proteins by formation of an isopeptide bond within or between polypeptide chains. It is also known as TGC, tTG, type II-, Gh, cytosolic-, liver-, endothelial-, erythrocyte-, cellular-transglutaminase. Different tissues and cell types express varying amounts of tissue transglutaminase with a markedly hugh expression in rheumatoid lesions. It is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.

Pathways: Tube Formation, Thromboxane A2 Receptor Signaling