TRIB3 anticorps (N-Term)

N° du produit ABIN1109329

Cet anticorps Lapin Polyclonal détecte spécifiquement TRIB3 dans WB, IHC (fro) et EIA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TRIB3 anticorps (N-Term) (ABIN1109329)

Antigène: TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIB3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Détail du produit anti-TRIB3 anticorps

Épitope: N-Term

Specificité: Reacts with Human 39 kDa TRIB-3 protein.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography on Protein A

Immunogène: Synthetic peptide derived from N-terminal domain of Human TRIB-3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in distilled water.

Buffer: 0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Détails sur TRIB3

Antigène: TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))

Autre désignation: TRIB3

Sujet: A novel inhibitor of cell division, Tribbles, blocks mitosis at a critical point in Drosophila morphogenesis. Recently, mammalian homologues of Tribbles (Trbs) have been identified that control mitogen-activated protein kinase (MAPK) activity. TRIB3 also known as TRB-3, SINK, and SKIP3 is a member of Trbs family. Overexpression of this protein inhibits NF-kB-dependent transcription induced by tumor necrosis factor (TNF) stimulation or its downstream signaling proteins but does not inhibit NF-kB translocation to the nucleus and binding to DNA. TRIB3/SKIP3 is also overexpressed in multiple human tumors and is regulated by hypoxia.Synonyms: NIPK, SKIP3, TRB-3, TRB3, Tribbles homolog 3

ID gène: 57761

NCBI Accession: NP_066981

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha