TRIP10 anticorps (Middle Region)

N° du produit ABIN1109339

Détail du produit anti-TRIP10 anticorps

Antigène: TRIP10 (Thyroid Hormone Receptor Interactor 10 (TRIP10))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Poisson zèbre (Danio rerio), Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIP10 est non-conjugé

Application: Western Blotting (WB)

Séquence: FEGSSEGTIS MAEGEDLSLM EEDKGDGWTR VRRKEGGEGY VPTSYLRVTL

Réactivité croisée (Details): Species reactivity (expected):Rat, Mouse, Bovine, Zebrafish, African clawed frog, RabbitSpecies reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogène: The immunogen for anti-TRIP10 antibody: synthetic peptide directed towards the middle region of human TRIP10.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Détails sur TRIP10

Antigène: TRIP10 (Thyroid Hormone Receptor Interactor 10 (TRIP10))

Autre désignation: TRIP10 (TRIP10 Produits)

Synonymes: anticorps CIP4, anticorps HSTP, anticorps STOT, anticorps STP, anticorps AI646975, anticorps Cip4, anticorps trip10, anticorps thyroid hormone receptor interactor 10, anticorps thyroid hormone receptor interactor 10a, anticorps TRIP10, anticorps Trip10, anticorps trip10a

Sujet: TRIP10 is required for translocation of GLUT4 to the plasma membrane in response to insulin signaling and to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. It binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules and also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. TRIP10 is further required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells and may be required for the lysosomal retention of FASLG/FASL.Synonyms: CIP4, Cdc42-interacting protein 4, Protein Felic, STOT, STP, Salt tolerant protein, TRIP-10, Thyroid receptor-interacting protein 10

ID gène: 9322

NCBI Accession: NP_004231