TUBB3 anticorps

N° du produit ABIN1109374

Cet anticorps Souris Monoclonal détecte spécifiquement TUBB3 dans WB, IP, IHC (fro) et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour TUBB3 anticorps (ABIN1109374)

Antigène: TUBB3 (Tubulin, beta 3 (TUBB3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TUBB3 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone: 3D9

Détail du produit anti-TUBB3 anticorps

Specificité: Reacts with Human 55 kDa TUBB3 protein. Cross reacts with Mouse, Rat and other species.

Purification: Affinity Chromatography on Protein A

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in distilled water

Concentration: 1 mg/mL

Buffer: PBS, None

Détails sur TUBB3

Antigène: TUBB3 (Tubulin, beta 3 (TUBB3))

Autre désignation: TUBB3 / TUBB4

Sujet: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non exchangeable site on the alpha-chain. Tubulin is a highly conserved protein with a molecular weight of ~50 kD. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton. The two main tubulin isoforms, α- and β-tubulin, are usually products of separate genes. The β-tubulin family includes six expressed genes that produce the polypeptide isoforms known as Classes I through VI, each of which have a distinct pattern of expression. Class III β-tubulin is found in neurons and mammalian testis cells and is widely used as a neuronal marker in developmental neurobiology, neoplasia, and stem cell research. Class III β-tubulin expression in neuronal and neuroblastic tumors is differentiation dependent, and its expression in certain non-neuronal neoplasms has been associated with poor prognosis and/or resistance to chemotherapy.Synonyms: Tubulin beta-3 chain, Tubulin beta-4, Tubulin beta-III

ID gène: 10381

Pathways: Dynamique des Microtubules, M Phase