TUBB3 anticorps

N° du produit ABIN1109374

Cet anticorps Souris Monoclonal détecte spécifiquement TUBB3 dans WB, IP, IHC (fro) et EIA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour TUBB3 anticorps (ABIN1109374)

Antigène: TUBB3 (Tubulin, beta 3 (TUBB3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TUBB3 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone: 3D9

Détail du produit anti-TUBB3 anticorps

Specificité: Reacts with Human 55 kDa TUBB3 protein. Cross reacts with Mouse, Rat and other species.

Purification: Affinity Chromatography on Protein A

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in distilled water

Concentration: 1 mg/mL

Buffer: PBS, None

Détails sur TUBB3

Antigène: TUBB3 (Tubulin, beta 3 (TUBB3))

Autre désignation: TUBB3 / TUBB4

Sujet: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non exchangeable site on the alpha-chain. Tubulin is a highly conserved protein with a molecular weight of ~50 kD. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton. The two main tubulin isoforms, α- and β-tubulin, are usually products of separate genes. The β-tubulin family includes six expressed genes that produce the polypeptide isoforms known as Classes I through VI, each of which have a distinct pattern of expression. Class III β-tubulin is found in neurons and mammalian testis cells and is widely used as a neuronal marker in developmental neurobiology, neoplasia, and stem cell research. Class III β-tubulin expression in neuronal and neuroblastic tumors is differentiation dependent, and its expression in certain non-neuronal neoplasms has been associated with poor prognosis and/or resistance to chemotherapy.Synonyms: Tubulin beta-3 chain, Tubulin beta-4, Tubulin beta-III

ID gène: 10381

Pathways: Dynamique des Microtubules, M Phase