PRSS1 anticorps

N° du produit ABIN7101954

Détail du produit anti-PRSS1 anticorps

Antigène: PRSS1 (Protease, serine, 1 (Trypsin 1) (PRSS1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PRSS1 est non-conjugé

Application: Enzyme Immunoassay (EIA)

Specificité: Human pancreatic trypsin. Recognizes specifically pancreatic trypsin. Does not cross react with Pancreatic Chymotrypsin.

Purification: Protein G affinity chromatography.

Immunogène: Purified human pancreatic trypsin

Clone: 401

Isotype: IgG2b

Information d'application

Indications d'application: ELISA: May be used in immunoassays to detect and quantitate Pancreatic Trypsin.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL (OD 280 nm)

Buffer: PBS, pH 7.4 without preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Détails sur PRSS1

Antigène: PRSS1 (Protease, serine, 1 (Trypsin 1) (PRSS1))

Autre désignation: Trypsin-1 / PRSS1 (PRSS1 Produits)

Synonymes: anticorps TRP1, anticorps TRY1, anticorps TRY4, anticorps TRYP1, anticorps LOC397853, anticorps Trypsin, anticorps wu:fb57g08, anticorps zgc:109701, anticorps Dvtry-1, anticorps dvir_GLEANR_6853, anticorps DvirGJ21500, anticorps GJ21500, anticorps Try1, anticorps PTRYI, anticorps RATPTRYI, anticorps Try-1, anticorps Trygn16, anticorps protease, serine 1, anticorps protease, serine 1 L homeolog, anticorps trypsin-1, anticorps Trypsin-1, anticorps trypsin I, anticorps protease, serine 1 (trypsin 1), anticorps protease, serine, 1 (trypsin 1), anticorps PRSS1, anticorps prss1.L, anticorps prss1, anticorps CpipJ_CPIJ000708, anticorps CpipJ_CPIJ007079, anticorps CpipJ_CPIJ007080, anticorps CpipJ_CPIJ012156, anticorps CpipJ_CPIJ016225, anticorps CpipJ_CPIJ016619, anticorps CpipJ_CPIJ018339, anticorps Dvir\Try1, anticorps trp-i, anticorps Prss1

Sujet: The human pancreas secretes three different isoforms of the inactive trypsinogen into the small intestine, namely cationic trypsinogen, anionic trypsinogen (the two major isoforms) and mesotrypsinogen (a minor isoform). In the small intestine, each isoform is cleaved by Enterokinase into its active form, Trypsin-1, Trypsin-2 and Trypsin-3, respectively. All trypsins are members of the serine protease trypsin family. The activated trypsins go on to activate other protease zymogens and play a role in the autoactivation of trypsinogens. This suggests an important role for trypsins in digestion. Mutations in the gene encoding Trypsin-1 that stimulate its activity are associated with autosomal dominant hereditary pancreatitis (HCP), also known as chronic pancreatitis (CP), a disease characterized by persistent, severe abdominal pain due to calcifications of the parenchyma, pancreatic stones, cysts and pancreatic head enlargement. Trypsin-3, also known as Trypsin-4, is expressed in the brain in addition to the pancreas.Synonyms: Beta-trypsin, Cationic trypsinogen, Serine protease 1, TRP1, TRY1, TRYP1, Trypsin I

ID gène: 5644

NCBI Accession: NP_002760

UniProt: P07477