PDGFRB anticorps

N° du produit ABIN111188

L’anticorps anti-PDGFRB Monoclonal Souris est utilisé pour la détection de PDGFRB dans des échantillons de Humain et Singe. Il a été validé pour WB, IF, IHC (p) et IP.

Aperçu rapide pour PDGFRB anticorps (ABIN111188)

Antigène: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Reactivité: Humain, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PDGFRB est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Clone: 21-72

Détail du produit anti-PDGFRB anticorps

Specificité: This antibody is specific for the extracellular domain of the PDGF receptor beta subunit. This was confirmed in binding studies using several different cell lines and by its ability to immunoprecipitate PDGF receptor beta complexed with 125I-PDGF-BB. This antibody does not recognize PDGF receptor alpha. Binding of PDGF-BB induces receptor homodimerization or heterodimerization with PDGF receptor alpha.

Purification: Affinity chromatography on Protein G

Immunogène: Human skin fibroblast cell membrane extracts.

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry: 25 μg/mL. Immunoprecipitation. Western Blot. Immunohistochemistry on frozen sections. Immunohistochemistry on paraffin sections: 25 μg/mL. Recommended Positive Control: Human breast cancer tissue.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PDGFRB

Antigène: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Autre désignation: CD140b / PDGFRB

Sujet: PDGF receptor beta is a member of the class III receptor tyrosine kinase family that also includes M-CSF receptor, SCF receptor and Flt-3.Synonyms: Beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, PDGF Receptor beta, PDGF-R-beta

ID gène: 5159

NCBI Accession: NP_002600

UniProt: P09619

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling