Annexin a1 anticorps (N-Term)

N° du produit ABIN1112715

Cet anticorps anti-Annexin a1 est un anticorps Lapin Polyclonal détectant Annexin a1 dans WB. Adapté pour Chien et Singe.

Aperçu rapide pour Annexin a1 anticorps (N-Term) (ABIN1112715)

Antigène: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Reactivité: Chien, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Annexin a1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Annexin a1 anticorps

Épitope: N-Term

Specificité: Detect endogenous level of total Annexin A1 protein.

Immunogène: A synthetic peptide (conjugated to KLH) corresponding to N-terminal residues of human Annexin A1.

Isotype: IgG

Information d'application

Indications d'application: Western Blot (1:1000) Other applications have not been tested. The optimal dilutions should be determined by end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Stock: -20 °C

Stockage commentaire: Store at -20 °C for 1 year. Avoid repeated freeze and thaw cycles.

Date de péremption: 12 months

Détails sur Annexin a1

Antigène: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Autre désignation: Annexin A1

Sujet: Annexin A1 / Annexin I also known as lipocortin I is a protein that in humans is encoded by the ANXA1 gene. Annexin I belongs to the annexin family of Ca2+-dependent phospholipid-binding proteins that have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Annexin I has been of interest for use as a potential anticancer drug. It inhibits the NF- kappa B signal transduction pathway, which is exploited by cancerous cells to proliferate and avoid apoptosis. ANXA1 inhibits the activation of NF-kappaB by binding to the p65 subunit.

Pathways: Hormone Transport