TIE1 anticorps

N° du produit ABIN1112934

Cet anticorps anti-TIE1 est un anticorps Lapin Polyclonal détectant TIE1 dans WB, ICC et FACS. Adapté pour Souris et Rat.

Aperçu rapide pour TIE1 anticorps (ABIN1112934)

Antigène: TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIE1 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Détail du produit anti-TIE1 anticorps

Purification: affinity purified

Isotype: IgG

Information d'application

Indications d'application: WB (1:5000), ICC (1:100-500), Flow Cyt (1:10-100). Other applications have not been tested. The optimal dilutions should be determined by end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Date de péremption: 12 months

Détails sur TIE1

Antigène: TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))

Autre désignation: Tyrosine-Protein Kinase Receptor TIE1

Sujet: Tyrosine kinase with immunoglobulin-like and EGF-like domains 1, TIE1 is an angiopoietin receptor which in humans is encoded by the TIE1 gene. 1 The receptor tyrosine kinase Tie1 is expressed in both vascular endothelial cells and immature hematopoietic cells. 2 TIE1 upregulates the cell adhesion molecules (CAMs) VCAM-1, E-selectin, and ICAM-1 through a p38-dependent mechanism. Attachment of monocyte derived immune cells to endothelial cells is also enhanced by TIE1 expression. TIE1 has a proinflammatory effect and may play a role in the endothelial inflammatory diseases such as atherosclerosis. 3

Pathways: Signalisation RTK