APOA1 anticorps
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- Antigène Voir toutes APOA1 Anticorps
- APOA1 (Apolipoprotein A-I (APOA1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp APOA1 est non-conjugé
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Application
- Radioimmunoassay (RIA), Enzyme Immunoassay (EIA)
- Specificité
- Recognizes Apolipoprotein A1 (Apo AI). No cross reactivity with Apo A-II or Apo B.Aff. Const.:8 x 10e9
- Purification
- Protein A Chromatography.
- Immunogène
- Purified Human plasma Apo A-I
- Clone
- 1405
- Isotype
- IgG1
- Top Product
- Discover our top product APOA1 Anticorps primaire
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- Indications d'application
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Suitable for use in Competitive RIA or EIA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 3.47 mg/mL (OD280 nm, E1% = 14)
- Buffer
- PBS, pH 7.0 containing 0.02 % Sodium Azide as preservative.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light. Should it contain a precipitate we recommend microcentrifugation before use.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- APOA1 (Apolipoprotein A-I (APOA1))
- Autre désignation
- Apolipoprotein A I (APO AI) (APOA1 Produits)
- Synonymes
- anticorps Alp-1, anticorps Apoa-1, anticorps Brp-14, anticorps Ltw-1, anticorps Lvtw-1, anticorps Sep-1, anticorps Sep-2, anticorps Sep2, anticorps apoA-I, anticorps apoa, anticorps apoa1, anticorps cb49, anticorps wu:fb33f01, anticorps zgc:103718, anticorps MGC64335, anticorps MGC89745, anticorps Apo-AI, anticorps ApoA-I, anticorps APOA1, anticorps LOC100136573, anticorps apoa-i, anticorps ApoAI, anticorps apolipoprotein A1, anticorps apolipoprotein A-I, anticorps apolipoprotein A-Ia, anticorps apolipoprotein A-I S homeolog, anticorps apolipoprotein A4, anticorps APOA1, anticorps Apoa1, anticorps apoa1a, anticorps apoa1.S, anticorps apoa1, anticorps LOC100136573, anticorps apoa-i, anticorps apoa4
- Sujet
- Apolipoprotein A I promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A I is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77 amino acids, an 18 amino acid signal peptide is removed co-translationally and a 6 amino acid propeptide is cleaved post-translationally. Apolipoprotein A I is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease. The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I. The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases.Synonyms: APOA1, Apo-AI, ApoA-I, ApoAI
- ID gène
- 335
- NCBI Accession
- NP_000030
- UniProt
- P02647
- Pathways
- Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
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