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- Antigène Voir toutes CD68 Anticorps
- CD68 (CD68 Molecule (CD68))
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Reactivité
- Rat
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD68 est conjugé à/à la Biotin
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Application
- Flow Cytometry (FACS)
- Specificité
- CD68 antibody (Cat#BM4000B) recognises a single chain glycoprotein of 110 kDa that is expressed predominantly on the lysomal membrane of myeloid cells. Weak cell surface expression also occurs. The antigen is expressed by the majority of tissue macrophages, and weakly be peripheral blood granulocytes. Studies have shown that the antigen recognised by ED1 is the rat homologue of human CD68.
- Purification
- Affinity Chromatography on Protein A
- Immunogène
- Rat spleen cells
- Clone
- ED1
- Isotype
- IgG1
- Top Product
- Discover our top product CD68 Anticorps primaire
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- Indications d'application
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Flow Cytometry: Use 10 mLof neat antibody to label 10^6 cells in 100 μL. (Results maybe enhanced using membrane permeabilisation).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.1 mg/mL
- Buffer
- PBS, pH 7.2 with 0.09 % Sodium Azide as preservative and 1 % BSA as stabiliser
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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Low-dose indomethacin after ischemic acute kidney injury prevents downregulation of Oat1/3 and improves renal outcome." dans: American journal of physiology. Renal physiology, Vol. 297, Issue 6, pp. F1614-21, (2009) (PubMed).
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Low-dose indomethacin after ischemic acute kidney injury prevents downregulation of Oat1/3 and improves renal outcome." dans: American journal of physiology. Renal physiology, Vol. 297, Issue 6, pp. F1614-21, (2009) (PubMed).
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- Antigène
- CD68 (CD68 Molecule (CD68))
- Autre désignation
- CD68 (CD68 Produits)
- Synonymes
- anticorps Lamp4, anticorps Scard1, anticorps gp110, anticorps GP110, anticorps LAMP4, anticorps SCARD1, anticorps CD68 molecule, anticorps CD68 antigen, anticorps Cd68 molecule, anticorps CD68, anticorps Cd68
- Sujet
- The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells.Synonyms: Gp110, Macrophage marker, Macrosialin
- ID gène
- 287435
- NCBI Accession
- NP_001026808
- UniProt
- Q4FZY1
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