Iba1 anticorps (Biotin)

N° du produit ABIN112010

L’anticorps anti-Iba1 Monoclonal Souris est utilisé pour la détection de Iba1 dans des échantillons de Humain et Rat. Il a été validé pour IHC (p).

Aperçu rapide pour Iba1 anticorps (Biotin) (ABIN112010)

Antigène: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Iba1 est conjugé à/à la Biotin

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1022-5

Détail du produit anti-Iba1 anticorps (Biotin)

Specificité: Recognizes AIF-1. This antibody BM4114B reacts with activated Macrophages / Microglial cells.

Purification: Affinity Chromatography.

Immunogène: Purified Human recombinant AIF-1 Epitope is not further characterized.

Isotype: IgG2b

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Sections: 5 μg/mL (1/40). Pretreatment is not necessary. Suggested Positive Control: Human spleen. This antibody does not react on routinely processed Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore by adding 0.5 mL distilled water.

Concentration: 0.2 mg/mL

Buffer: PBS containing 5 mg/mL BSA as a stabilizer and 0.09 % Sodium Azide as a preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: This product is photosensitive and should be protected from light

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted Prior to and following reconstitution at 2-8 °C. DO NOT FREEZE!

Détails sur Iba1

Antigène: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Autre désignation: AIF1

Sujet: Allograft Inflammatory Factor-1 is a Ca2+-binding peptide produced by activated macrophages and microglial cells. It has been suggested that AIF-1 expression is associated with chronic inflammatory processes. AIF-1, like the Ca2+-binding peptides MRP8 and MRP14, is expressed by activated macrophages and might participate in a variety of pathogenic processes in the mammalian brain and in chronic transplant rejection. It has been shown to be expressed early and persistently in chronically rejecting cardiac allografts but not in cardiac syngrafts and host hearts. The recently described apoptosis-inducing factor AIF is not related to AIF-1.Synonyms: AIF-1, Allograft inflammatory factor 1, IBA1, Ionized Calcium-Binding Adapter Molecule 1, Protein G1

ID gène: 199

NCBI Accession: NP_001614

UniProt: P55008

Pathways: Smooth Muscle Cell Migration