Desmin anticorps

N° du produit ABIN112305

Cet anticorps anti-Desmin Monoclonal Souris (Clone D9) (ABIN112305) détecte spécifiquement Desmin dans WB, IHC (p) et IHC (fro). L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Poulet, Porc et Lapin.

Aperçu rapide pour Desmin anticorps (ABIN112305)

Antigène: Desmin (DES)

Reactivité: Humain, Rat, Souris, Poulet, Porc, Lapin

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Desmin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: D9

Détail du produit anti-Desmin anticorps

Specificité: D9 reacts exclusively with Desmin, which is expressed in smooth and striated muscle cells and their tumors e.g. rhabdomyosarcoma and leiomyosarcoma.

Réactivité croisée (Details): Species reactivity (tested):Chicken, Human, Mouse, Rabbit, Rat, Swine.

Purification: Purified

Immunogène: Desmin isolated from human leiomyoma.

Isotype: IgG1

Information d'application

Indications d'application: D9 is suitable for immunoblotting (1: 100 - 1: 1000) and immunohistochemistry on frozenand paraffin embedded tissues (recommended range is 1: 25 - 1: 200 forimmunohistochemistry with avidinbiotinylated horseradish peroxidase complex (ABC) asdetection reagent).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Desmin

Antigène: Desmin (DES)

Autre désignation: Desmin

Sujet: Desmin (53 kDa) exhibits a high degree of tissue specificity, its expression being predominantly confined to all types of muscle cells (cardiac, skeletal and smooth muscle). Regulation of desmin expression is stage and tissue-specific, since it is induced during terminal development of, for example, skeletal muscle cell differentiation. In skeletal en cardiac muscle cells desmin is localized in the Z-disk region and at the intercalated disk. The expression pattern of desmin in smooth muscle is much more heterogenous. Coexpression of vimentin and desmin has been observed in tumors derived from muscle tissue, i.e. rhabdomyosarcomas and leiomyosarcomas. Furthermore, during myocard dysfunction dramatic changes in the distribution of desmin have been observed.Synonyms: DES

ID gène: 1674

NCBI Accession: NP_001918

UniProt: P17661