Tissue factor anticorps
Aperçu rapide pour Tissue factor anticorps (ABIN112492)
Antigène
Voir toutes Tissue factor (F3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody is specific for an epitope within the extracellular domain, epitope locus I. It recognizes both the reduced and native non-reduced human and primate tissue factors. It does not inhibit coagulation or neutralize factor VII binding to CD142.
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Purification
- Affinity Chromatography on Protein G.
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Immunogène
- Denatured Tissue factor isolated from human brain by the Factor VII affinity method.
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Isotype
- IgG1
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Indications d'application
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ELISA. Western blot. Flow Cytometry. Immunofluorescence. Immunohistology on Frozen and Paraffin Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Phosphate buffered saline containing 0.09 % Sodium Azide as preservative and 200 mM Mannitol as stabilizer.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))
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Autre désignation
- CD142 / Tissue Factor
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Sujet
- CD142, also known as Tissue factor, is the membrane receptor for coagulation factors VII and VIIa and is the cell surface initiator of coagulation. It is the major molecule of this type and is criticial for controlling hemostasis, thrombosis and inflammation.Synonyms: Coagulation factor III, F3, TF, Thromboplastin
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ID gène
- 2152
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NCBI Accession
- NP_001984
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UniProt
- P13726
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Pathways
- Positive Regulation of Endopeptidase Activity, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
Antigène
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