CTXB anticorps (HRP)
Aperçu rapide pour CTXB anticorps (HRP) (ABIN112703)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody detects the beta subunit of Cholera toxin.
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Immunogène
- Purified Choleragenoid.
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Indications d'application
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Immunohistochemistry on frozen sections (1: 20 - 1: 200). ELISA (1: 200 - 1: 1000). Western blot (1: 20 - 1: 200).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1-2 mg/mL
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Buffer
- Phosphate buffered saline, pH 7.2, containing 0.002 % Thimerosal and 1 % Bovine serum albumin
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CTXB (CtxB Gene Product (CTXB))
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Autre désignation
- Cholera Enterotoxin Subunit B
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Sujet
- The Beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin Alpha subunit into cells. The holotoxin consists of a pentameric ring of Beta subunits whose central pore is occupied by the Alpha subunit. The Alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The Alpha subunit (and Cholera toxin) activate the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, VC_1456, ctxB, toxB
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ID gène
- 2613962
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NCBI Accession
- NP_231099
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UniProt
- P01556
Antigène
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