APOC3 anticorps (Biotin)
Aperçu rapide pour APOC3 anticorps (Biotin) (ABIN113012)
Antigène
Voir toutes APOC3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Binds to Apo CIII. No cross-reaction to Apo AI, Apo AII, Apo B-100, Apo CI, Apo CII and Apo E.
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Purification
- Human Apo CIII-Sepharose affinity column.
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Immunogène
- Purified human Apolipoprotein CIII
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Indications d'application
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Can be used to detect the existence of Apo CIII in plasma and lipoproteins, forimmunoassay and immunoblotting. Dilution for immunoblot and ELISA range: 8,000 to 30,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
- Reconstitutein 0.5 mL distilled water.
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Concentration
- 1.2 mg/mL
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Buffer
- 10 mM PBS, 0.15 M NaCl, pH 7.2 with 0.02 % sodium azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- APOC3 (Apolipoprotein C-III (APOC3))
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Autre désignation
- Apolipoprotein C III (Apo CIII)
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Sujet
- At least 9 distinct polymorphic forms of apolipoproteins are known. The apolipoproteins act as stabilizers of the intact lipoprotein particles. Quantitative measurements of HDL, LDL and VLDL particles in human serum are often used to estimate an individuals' relative risk of coronary heart disease. In addition, quantitative immunological measurements of certain apolipoproteins (especially A1 and B) have been suggested to be more accurate estimators of coronary heart disease than measurements of lipoprotein particles (especially HDL and LDL). Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. It inhibits lipoprotein lipase and hepatic lipase and it is thought to delay catabolism of triglyceride-rich particles. An increase in ap °C-III levels induces the development of hypertriglyceridemia.Synonyms: Apo-CIII, Ap °C-III, Ap °C3, Apolipoprotein C-III, Apolipoprotein C3
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ID gène
- 345
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NCBI Accession
- NP_000031
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UniProt
- P02656
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Pathways
- Carbohydrate Homeostasis, Lipid Metabolism
Antigène
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