OPRK1 anticorps (AA 346-380)

N° du produit ABIN113054

L’anticorps anti-OPRK1 Polyclonal Lapin est utilisé pour la détection de OPRK1 dans des échantillons de Rat. Il a été validé pour WB, IF, EIA et IHC (fro).

Aperçu rapide pour OPRK1 anticorps (AA 346-380) (ABIN113054)

Antigène: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OPRK1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-OPRK1 anticorps

Épitope: AA 346-380

Specificité: This antibody is Specific for the COOH terminal of the Opioid Receptor kappa (346-380). This antisera has been characterized by Western blotting, ELISA, and Cell Staining Techniques. Cross-reactivity: Rat Kappa Opioid Receptor (346-380): 100 % Rat Kappa Opioid Receptor: 70 % Delta Opioid Receptor (360-372): 0 % Delta Opioid Receptor: 0 % Mu Opioid Receptor (391-398): 0 % Mu Opioid Receptor: 0 %.

Immunogène: Peptide analogue of the carboxyl terminal of the Rat Kappa Opioid Receptor covalently attached to a carrier protein.

Information d'application

Indications d'application: Suitable for Immunocytochemical and Western Immunoblotting (whole rat brainhomogenate, at a dilution of 1/1,500). This antiserum has been found to stain specific cells in various regions of PLP fixed ratbrain sections known to express the kappa opioid receptor using ABC techniques at adilution of 1/5,000. These include the nucleus accumbens, olfactory tubercule, caudate putamen and portionsof the amygdala.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Restore with 0.1 mL of PBS which contains 10 mg/mL BSA or with additional buffer for more dilute antisera.

Agent conservateur: Azide free

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store (in aliquots) at -20 °C.

Détails sur OPRK1

Antigène: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Autre désignation: kappa Opioid Receptor

Sujet: Opioid is the term used to designate a group of compounds that are opium-like in their properties. These drugs have effects on perception of pain, consciousness, motor control, mood, and autonomic function, and can induce physical dependence. Pharmacological studies suggested that there are at least 3 major classes of opioid receptors, designated delta, kappa, and mu. They differ in their affinity for various opioid ligands and in their cellular distribution. Studies of the receptors in the mouse and rat show that they are structurally related and are members of the family of 7 transmembrane-spanning G protein-coupled receptors. The kappa opiod receptor inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. It is the receptor for beta-endorphin.Synonyms: KOR-1, KOR1, OPRK, OPRK1

ID gène: 29335

NCBI Accession: NP_058863

UniProt: P34975