CTXB anticorps

N° du produit ABIN113086

Cet anticorps Lapin Polyclonal détecte spécifiquement CTXB dans EIA et IP. Il présente une réactivité avec des échantillons de Vibrio cholerae.

Aperçu rapide pour CTXB anticorps (ABIN113086)

Antigène: CTXB (CtxB Gene Product (CTXB))

Reactivité: Vibrio cholerae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTXB est non-conjugé

Application: Enzyme Immunoassay (EIA), Immunoprecipitation (IP)

Détail du produit anti-CTXB anticorps

Specificité: Beta subunit of Cholera toxin.

Purification: Protein A chromatography.

Immunogène: Purified choleragenoid.

Information d'application

Indications d'application: ELISA: Titer: >1: 1,000. Also suitable for conjugation purposes. Immunoprecipitates toxin in gel techniques.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 4-5 mg/mL (OD280nm, E0.1% = 1.4)

Buffer: 0.01 M PBS, pH 7.2 with 0.09 % sodium azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CTXB

Antigène: CTXB (CtxB Gene Product (CTXB))

Autre désignation: Cholera Enterotoxin Subunit B

Sujet: The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge. The A subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, VC_1456, ctxB, toxB

ID gène: 2613962

NCBI Accession: NP_231099

UniProt: P01556