C5 anticorps

N° du produit ABIN113312

Détail du produit anti-C5 anticorps

Antigène: C5 (Complement Component 5 (C5))

Reactivité: Humain

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp C5 est non-conjugé

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunodiffusion (ID)

Specificité: Gives a single arc when tested by IEP against fresh Human plasma. Identity has been confirmed by Double Diffusion against fresh Human plasma and a known anti-Human C5.

Purification: Ion Exchange Chromatography

Immunogène: Human C5 purified from plasma

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry: 1/20-1/200 (as a guide). Immunodiffusion.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Glycine buffered saline, pH 7.4, containing 0.09 % Sodium Azide, 0.1 % EACA, 0.01 % Benzamidine and 1 mM EDTA

Agent conservateur: Sodium azide, Benzamidine, EACA

Précaution d'utilisation: This product contains Sodium azide, Benzamidine and EACA: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid multiple freeze/thaw cycles.

Détails sur C5

Antigène: C5 (Complement Component 5 (C5))

Autre désignation: Complement C5 (C5 Produits)

Synonymes: anticorps C5, anticorps LOC565774, anticorps C5a, anticorps C5b, anticorps CPAMD4, anticorps Hc, anticorps RGD1561905, anticorps He, anticorps complement C5, anticorps complement component 5, anticorps hemolytic complement, anticorps C5, anticorps c5, anticorps Hc

Sujet: C5 is synthesised in the liver as a single polypeptide chain. Before secretion the molecule is glycosylated and secreted into plasma as a 190 kDa glycoprotein consisting of a disulphide linked alpha-chain (111 kDa) and beta-chain (75 kDa). C5 precursor is first processed by the removal of 4 basic residues, forming two chains, beta and alpha, linked by a disulfide bond. C5 convertase activates C5 by cleaving the alpha chain, releasing C5a anaphylatoxin and generating C5b (beta chain + alpha' chain).Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, CPAMD4, Complement component 5

ID gène: 727

NCBI Accession: NP_001726

UniProt: P01031

Pathways: Système du Complément, Carbohydrate Homeostasis