ITM2B
Reactivité: Humain
Hôte: Lapin
Polyclonal
FITC
Indications d'application
Suitable for Western blot and not recommended for Immunohistochemistry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
1.0 mg/mL
Buffer
Phosphate buffered saline, pH 7.2 with 0.09 % sodium azide as preservative.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody at 2-8 °C for one month or (following reconstitution in aliquots) at -20 °C for longer.
Antigène
ITM2B
(Integral Membrane Protein 2B (ITM2B))
Autre désignation
ITM2B
Sujet
This antibody has been developed against the amino terminal sequence of BRI protein (ITM2B), a type-II single spanning transmembrane protein found in brain and other tissues. Mutation of the BRI gene with concomitant elongation of the carboxy terminus and its cleavage by the protease furin has been shown to lead to deposition of a protein fragment that may be involved in the pathogenesis of familial British dementia.Synonyms: BRI, BRI2, ITM2B, Integral membrane protein 2B, Transmembrane protein BRI