ENOS anticorps

N° du produit ABIN113627

Détail du produit anti-ENOS anticorps

Antigène: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ENOS est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Specificité: Specific for the amino terminal of eNOS. It recognizes the non-myrisylated form best, but does cross-react ~50 % with the myristylated form of eNOS. Also recognizes Rat eNOS. Cross-reactivity: eNOS (2-11 Cys12): 100 % Recombinant eNOS (NOS type III): 100 % eNOS (cap-2-11Cys12): 50 % Recombinant myristylated eNOS (myristylated NOS type III): 0 % Recombinant hnNOS (NOS type I): 0 % Recombinant hiNOS (NOS type II): 0 %

Réactivité croisée (Details): Species reactivity (tested):Human and Rat.

Immunogène: eNOS (2-11 Cys12) covalently attached to a carrier protein

Information d'application

Indications d'application: Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Restore with 0.1 mL of PBS which contains 10 mg/mL BSA or with additional buffer for more dilute antibody.

Agent conservateur: Azide free

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!. Avoid prolonged exposure to light.

Détails sur ENOS

Antigène: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Autre désignation: NOS3 (NOS3 Produits)

Synonymes: anticorps ECNOS, anticorps eNOS, anticorps 2310065A03Rik, anticorps Nos-3, anticorps ecNOS, anticorps EC-NOS, anticorps NOSIII, anticorps cNOS, anticorps NOS, anticorps NOS3, anticorps eNos, anticorps ENOS, anticorps nitric oxide synthase 3, anticorps nitric oxide synthase 3, endothelial cell, anticorps NOS3, anticorps Nos3, anticorps nos3

Sujet: Nitric oxide synthase NOS oxidizes a guanidine nitrogen of arginine releasing nitric oxide in the form of a free radical and citrulline. Nitric oxide thus generated acts as a messenger in diverse functions including vasodilation neurotransmission, anti tumor and anti pathogenic activities. NOS is classified under three types: neuronal NOS (nNOS) or brain NOS (bNOS), inducible NOS (iNOS) or macrophage NOS (mNOS), and endothelial NOS (eNOS). eNOS is a calcium/calmodulin dependent enzyme which undergoes several post translational modifications, including acylation with myristate and palmitate, and phosphorylation on numerous residues. As with the other members of the NOS family, eNOS derives the diffusible multifunctional second messenger NO from L arginine through a series of reactions in which L citrulline is an intermediate. eNOS plays an important role in controlling vascular tone, platelet aggregation, and cardiac myocyte function.Synonyms: Constitutive NOS, EC-NOS, Endothelial NOS, NOS type III, Nitric oxide synthase, eNOS, endothelial

ID gène: 4846

NCBI Accession: NP_000594

UniProt: P29474

Pathways: ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling