KRT17 anticorps
Aperçu rapide pour KRT17 anticorps (ABIN114619)
Antigène
Voir toutes KRT17 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Clone E3 reacts with Cytokeratin 17 in basal layers of pseudo-stratified and transitional epithelia.
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Réactivité croisée (Details)
- Species reactivity (tested):Human, Rat.
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Purification
- Purified
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Immunogène
- A cytoskeletal preparation from rat colon
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Isotype
- IgG2b
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Indications d'application
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Immunoblotting (1: 100 - 1: 1000). Immunocytochemistry. Immunohistochemistry on frozen and paraffin-embedded tissues (1: 25- 1: 200 forimmunohistochemistry with avidin-biotinylated horseradish peroxidase complec (ABC) asdetection regant). Flow cytometry (1: 25-1: 200)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS, 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- KRT17 (Keratin 17 (KRT17))
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Autre désignation
- Cytokeratin 17
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Sujet
- Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immuno-histochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.Synonyms: CK17, Cytokeratin-17, K17, KRT17, Keratin 17, Keratin type I cytoskeletal 17, Keratin-17
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Poids moléculaire
- 46 kDa
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ID gène
- 3872
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NCBI Accession
- NP_000413
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UniProt
- Q04695
Antigène
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