FLT3LG anticorps (Biotin)

N° du produit ABIN116011

Détail du produit anti-FLT3LG anticorps (Biotin)

Antigène: FLT3LG (Fms-Related tyrosine Kinase 3 Ligand (FLT3LG))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FLT3LG est conjugé à/à la Biotin

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: Recognizes Human Flt3-Ligand

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography.

Immunogène: Highly pure (>98%) recombinant Human Flt3-ligand.

Information d'application

Indications d'application: ELISADirect: To detect Human hFlt3-ligand by direct ELISA (using 100 μL/well antibody solution) aconcentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonalantibody, in conjunction with compatible secondary reagents, allows the detection of atleast 0.2-0.4 ng/well of recombinant Human Flt3-ligand. Sandwich: To detect Human Flt3-ligand by Sandwich ELISA (using 100 μL/well antibodysolution) a concentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylatedpolyclonal antibody, in conjunction with Polyclonal Anti-Human Flt3-ligand (PP1008P1 orPP1008P2) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well ofrecombinant Human Flt3-ligand. Western Blot: To detect hFlt3-ligand by Western Blot analysis this antibody can be used ata concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS, pH 7.2 without preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing. Centrifuge vial prior to opening.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Détails sur FLT3LG

Antigène: FLT3LG (Fms-Related tyrosine Kinase 3 Ligand (FLT3LG))

Autre désignation: Flt3 Ligand (FLT3LG Produits)

Synonymes: anticorps Flt3lg, anticorps Ly72L, anticorps FL, anticorps FLT3L, anticorps Vegfr3, anticorps fms related tyrosine kinase 3 ligand, anticorps FMS-like tyrosine kinase 3 ligand, anticorps fms-related tyrosine kinase 4, anticorps fms-related tyrosine kinase 3 ligand, anticorps FLT3LG, anticorps Flt3l, anticorps Flt4, anticorps Flt3lg

Sujet: Flt3 ligand is a ligand for the FLT3 tyrosine kinase receptor and belongs to a small group of growth factors that regulate proliferation of early hematopoietic cells. Multiple isoforms of Flt3 ligand have been identified. The predominant form is the transmembrane form, which is biologically active on the cell surface. When proteolytically cleaved the transmembrane isoform generates a soluble form, which is also biologically active. Flt3 ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3 ligand alone cannot stimulate proliferation, but synergizes well with other CSFs and interleukins to induce growth and differentiation. hflt3-Ligand (flk2-ligand) stimulates the proliferation and colony formation of certain bone marrow precursor cells including CD34+ cells.Synonyms: FLT3LG, Flt3L, SL cytokine, fms-related tyrosine kinase 3 ligand

ID gène: 2323

NCBI Accession: NP_001450

UniProt: P49771

Pathways: Signalisation RTK