Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

CXCL12 anticorps (Biotin)

CXCL12 Reactivité: Humain WB, EIA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN116227
  • Antigène Voir toutes CXCL12 Anticorps
    CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))
    Reactivité
    • 66
    • 23
    • 19
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 81
    • 9
    • 5
    • 2
    Lapin
    Clonalité
    • 84
    • 13
    Polyclonal
    Conjugué
    • 44
    • 15
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CXCL12 est conjugé à/à la Biotin
    Application
    • 75
    • 38
    • 34
    • 13
    • 13
    • 11
    • 9
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificité
    Recognizes Stromal Cell Derived Factor-1 alpha (SDF-1 alpha).
    Purification
    Affinity Chromatography.
    Immunogène
    Highly pure (>98%) E.coli derived recombinant Human SDF1-alpha.
    Top Product
    Discover our top product CXCL12 Anticorps primaire
  • Indications d'application
    ELISA: To detect hSDF-1alpha by direct ELISA (using 100 μL/well antibody solution) aconcentration of 0.25 - 1.0 μg/mL of this antibody is required. This antibody, in conjunctionwith compatible secondary reagents, allows the detection of at least 0.2 - 0.4 ng/well ofrecombinant hSDF-1alpha. To detect hSDF-1alpha by sandwich ELISA (using 100 μL/well antibody solution) aconcentration of 0.25 - 1.0 μg/mL of this antibody is required. This antibody, in conjunctionwith a polyclonal Anti-Human SDF-1alpha (PP1067P) as a capture antibody, allows thedetection of at least 0.2 - 0.4 ng/well of recombinant hSDF-1alpha. Western Blot: To detect hSDF-1alpha by Western Blot analysis this antibody can be used at aconcentration of 0.1 - 0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hSDF-1alpha is 1.5 - 3.0 ng/lane, under either reducingor non-reducing conditions.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.
    Buffer
    PBS, pH 7.2 without preservatives.
    Agent conservateur
    Without preservative
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • Schlaepfer, Audigé, Joller, Speck: "TLR7/8 triggering exerts opposing effects in acute versus latent HIV infection." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 5, pp. 2888-95, (2006) (PubMed).

  • Antigène
    CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))
    Autre désignation
    CXCL12 / SDF1 (CXCL12 Produits)
    Synonymes
    anticorps IRH, anticorps PBSF, anticorps SCYB12, anticorps SDF1, anticorps TLSF, anticorps TPAR1, anticorps CINC-1, anticorps Gro1, anticorps Pbsf, anticorps Scyb12, anticorps Sdf1, anticorps Tlsf, anticorps Tpar1, anticorps Fsp, anticorps KC, anticorps Mgsa, anticorps N51, anticorps Scyb1, anticorps gro, anticorps sdf-1, anticorps sdf1, anticorps xSDF-1, anticorps SDF-1, anticorps cxcl12, anticorps sdf-1a, anticorps sdf1a, anticorps wu:fa55e10, anticorps wu:fc16h12, anticorps wu:fj84c02, anticorps C-X-C motif chemokine ligand 12, anticorps C-X-C motif chemokine ligand 1, anticorps chemokine (C-X-C motif) ligand 12, anticorps chemokine (C-X-C motif) ligand 1, anticorps C-X-C motif chemokine ligand 12 L homeolog, anticorps chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1), anticorps CXCL12, anticorps cxcl12, anticorps Cxcl1, anticorps Cxcl12, anticorps cxcl12.L, anticorps cxcl12a
    Sujet
    SDF1 alpha and 1 beta are small cytokines that belong to the intercrine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF or IL1. SDF1 alpha has been shown to be chemotactic for lymphocytes and is recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV1 entry into T cells. SDF-1 binding to CXCR4 inhibits HIV1 entry.Synonyms: C-X-C motif chemokine 12, IRH, Intercrine reduced in hepatomas, PBSF, Pre-B cell growth-stimulating factor, SDF1A, SDF1B, Stromal cell-derived factor 1, hIRH
    ID gène
    6387
    NCBI Accession
    NP_000600
    UniProt
    P48061
    Pathways
    Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling
Vous êtes ici:
Support technique