FGF17 anticorps
Aperçu rapide pour FGF17 anticorps (ABIN116375)
Antigène
Voir toutes FGF17 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody recognizes FGF-17
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Purification
- Affinity Chromatography employing immobilized Human FGF-17 matrix.
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Immunogène
- Highly pure (>98%) recombinant Human FGF-17
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Indications d'application
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Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofHuman FGF-17 (200.0 ng/mL), a concentration of 2.1-3.2 μg/mL of this antibody is required. Sandwich ELISA: To detect Human FGF-17 by Sandwich ELISA (using 100 μL/well antibodysolution) a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinitypurified antibody, in conjunction with Biotinylated anti-Human FGF-17 (PP1130B1 orPP1130B2) as Detection antibody, allows the detection of 0.2-0.4 ng/well of recombinantHuman FGF-17. Western Blot: To detect Human FGF-17 by Western Blot analysis this antibody can be usedat a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondaryreagents the detection limit for recombinant Human FGF-17 is 1.5-3.0 ng/lane, under eitherreducing or non-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Reconstitution
- Restore in sterile Water to a concentration of 0.1-1.0 mg/mL.
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Buffer
- PBS, pH 7.2 without preservatives.
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
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- FGF17 (Fibroblast Growth Factor 17 (FGF17))
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Autre désignation
- FGF17
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Sujet
- FGF17 belongs to the heparin-binding growth factors family. It may be a signaling molecule in the induction and patterning of the embryonic brain and is preferentially expressed in the embryonic brain. There are two named isoforms.Synonyms: FGF-17, Fibroblast growth factor 17
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ID gène
- 8822
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NCBI Accession
- NP_003858
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UniProt
- O60258
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Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Antigène
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