Notch1 anticorps (Biotin)

N° du produit ABIN1169009

L’anticorps anti-Notch1 Monoclonal Rat est utilisé pour la détection de Notch1 dans des échantillons de Souris. Il a été validé pour FACS.

Aperçu rapide pour Notch1 anticorps (Biotin) (ABIN1169009)

Antigène: Notch1 (NOTCH1) (Notch 1 (NOTCH1))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Notch1 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Clone: 22E5

Détail du produit anti-Notch1 anticorps (Biotin)

Fonction: anti-Notch1 (mouse), mAb (22E5) (Biotin)

Specificité: Recognizes endogenous mouse Notch-1 receptor.

Attributs du produit: Monoclonal Antibody. Recognizes endogenous mouse Notch-1 receptor. Isotype: Rat IgG2akappa. Clone: 2.20E+06. Applications: FACS. Liquid. In PBS containing 0.02 % sodium azide. Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins.

Purification: Purified from concentrated hybridoma tissue culture supernatant.

Pureté: >95 % (SDS-PAGE)

Immunogène: Recombinant mouse Notch1:Fc (AG-40B-0109).

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: In PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Détails sur Notch1

Antigène: Notch1 (NOTCH1) (Notch 1 (NOTCH1))

Autre désignation: Notch1

Sujet:

Alternate Names/Synonyms: Neurogenic Locus Notch Homolog Protein 1, Motch A, mT14, p300

Product Description: Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins.

UniProt: Q01705

Pathways: Signalisation Notch, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development