TRIB3 anticorps (AA 112-125)

N° du produit ABIN1169021

L’anticorps anti-TRIB3 Polyclonal Lapin est utilisé pour la détection de TRIB3 dans des échantillons de Humain. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour TRIB3 anticorps (AA 112-125) (ABIN1169021)

Antigène: TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIB3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-TRIB3 anticorps

Épitope: AA 112-125

Fonction: anti-TRB-3 (human), pAb

Specificité: Recognizes human TRB-3. Detects a band of ~28 kDa by Western blot (predicted 39 kDa).

Attributs du produit: Polyclonal Antibody. Recognizes human TRB-3. Detects a band of ~28 kDa by Western blot (predicted 39 kDa). Source: Rabbit. Applications: ELISA, IHC, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. Tribbles homolog 3 (TRB-3) is a pseudokinase, shown to act as a potent negative regulator of PPARgamma, a master regulator of adipocyte differentiation, and to control adipogenesis. It disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. It interacts also with the NF-kappaB transactivator p65 RELA. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells.

Stérilité: 0.2 μm filtered

Immunogène: Synthetic peptide corresponding to aa 112-125 (A112RLPPHKHVARPTE125) of human TRB-3.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Agent conservateur: Without preservative

Conseil sur la manipulation: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire:

+4°C

-20°C

Stable for at least 6 months after receipt when stored at -20°C.

Date de péremption: 6 months

Détails sur TRIB3

Antigène: TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))

Autre désignation: TRB-3

Sujet:

Alternate Names/Synonyms: Tribbles Homolog 3, Neuronal Cell death-inducible Putative Kinase, SINK, p65-interacting Inhibitor of NF-kappaB

Product Description: Tribbles homolog 3 (TRB-3) is a pseudokinase, shown to act as a potent negative regulator of PPARgamma, a master regulator of adipocyte differentiation, and to control adipogenesis. It disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. It interacts also with the NF-kappaB transactivator p65 RELA. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells.

UniProt: Q96RU7

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha