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TRIB3 anticorps (AA 112-125)

TRIB3 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1169021
  • Antigène Voir toutes TRIB3 Anticorps
    TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
    Épitope
    • 16
    • 12
    • 11
    • 8
    • 8
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 112-125
    Reactivité
    • 68
    • 28
    • 22
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 75
    • 5
    Lapin
    Clonalité
    • 75
    • 5
    Polyclonal
    Conjugué
    • 41
    • 7
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TRIB3 est non-conjugé
    Application
    • 57
    • 43
    • 14
    • 13
    • 13
    • 13
    • 12
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificité
    Recognizes human TRB-3. Detects a band of ~28 kDa by Western blot (predicted 39 kDa).
     Réactivité croisée
    Humain
    Stérilité
    0.2 μm filtered
    Immunogène
    Synthetic peptide corresponding to aa 112-125 (A112RLPPHKHVARPTE125) of human TRB-3.
    Top Product
    Discover our top product TRIB3 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
    Agent conservateur
    Without preservative
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Date de péremption
    6 months
  • Antigène
    TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
    Autre désignation
    TRB-3 (TRIB3 Produits)
    Synonymes
    anticorps zgc:76966, anticorps TRIB3, anticorps C20orf97, anticorps NIPK, anticorps SINK, anticorps SKIP3, anticorps TRB3, anticorps Ifld2, anticorps Nipk, anticorps TRB-3, anticorps Trb3, anticorps tribbles pseudokinase 3, anticorps trib3, anticorps TRIB3, anticorps Trib3
    Sujet
    Tribbles homolog 3 (TRB-3) is a pseudokinase, shown to act as a potent negative regulator of PPARgamma, a master regulator of adipocyte differentiation, and to control adipogenesis. It disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. It interacts also with the NF-kappaB transactivator p65 RELA. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells.
    UniProt
    Q96RU7
    Pathways
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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