IL23A anticorps

N° du produit ABIN1169135

L’anticorps anti-IL23A Monoclonal Rat est utilisé pour la détection de IL23A dans des échantillons de Humain. Il a été validé pour WB et ELISA.

Aperçu rapide pour IL23A anticorps (ABIN1169135)

Antigène: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Reactivité: Humain

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL23A est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: I 178G

Détail du produit anti-IL23A anticorps

Fonction: anti-IL-23p19 (human), mAb (I 178G)

Specificité: Recognizes human IL-23p19.

Attributs du produit: Monoclonal Antibody. Recognizes human IL-23p19. Isotype: Rat IgG2akappa. Clone: I 178G. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. IL-23p19 associates with IL-12b to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 binds to an heterodimeric receptor complex composed of IL-12RB1 and IL-23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Stérilité: 0.2 μm filtered

Immunogène: Recombinant human IL-23p19.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Agent conservateur: Without preservative

Conseil sur la manipulation: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Détails sur IL23A

Antigène: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Autre désignation: IL-23p19

Sujet:

Alternate Names/Synonyms: Interleukin-23 Subunit p19, Interleukin-23 Subunit alpha, IL-23-A

Product Description: IL-23p19 associates with IL-12b to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 binds to an heterodimeric receptor complex composed of IL-12RB1 and IL-23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

UniProt: Q9NPF7

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation