IL23A anticorps (AA 33-67)
Aperçu rapide pour IL23A anticorps (AA 33-67) (ABIN6242802)
Antigène
Voir toutes IL23A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- AA 33-67
-
Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
Immunogène
- This IL23A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 33-67 amino acids from the Central region of human IL23A.
-
Isotype
- Ig Fraction
-
-
-
-
Indications d'application
- WB: 1:2000. FC: 1:25
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Date de péremption
- 6 months
-
-
- IL23A (Interleukin 23, alpha subunit p19 (IL23A))
-
Autre désignation
- IL23A
-
Sujet
- Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak- Stat signaling cascade, stimulates memory rather than naive T- cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
-
Poids moléculaire
- 20730
-
UniProt
- Q9NPF7
-
Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
Antigène
-