IDO1 anticorps

N° du produit ABIN1169197

Cet anticorps Souris Monoclonal détecte spécifiquement IDO1 dans WB, ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour IDO1 anticorps (ABIN1169197)

Antigène: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IDO1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: ID 177

Détail du produit anti-IDO1 anticorps

Specificité: Recognizes human IDO. Detects a band of ~45 kDa by Western blot.

Réactivité croisée: Humain

Réactivité croisée (Details): Other species not tested.

Stérilité: 0.2 μm filtered

Immunogène: Recombinant human IDO.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Détails sur IDO1

Antigène: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Autre désignation: IDO

Sujet: IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T-cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T-cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.

UniProt: P14902

Pathways: Activated T Cell Proliferation