NMNAT2 anticorps

N° du produit ABIN1169223

Cet anticorps anti-NMNAT2 Polyclonal Cobaye (ABIN1169223) détecte spécifiquement NMNAT2 dans ELISA, WB et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour NMNAT2 anticorps (ABIN1169223)

Antigène: NMNAT2 (Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2))

Reactivité: Humain

Hôte: Cobaye

Clonalité: Polyclonal

Conjugué: Cet anticorp NMNAT2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-NMNAT2 anticorps

Fonction: anti-NMNAT2 (human), pAb

Specificité: Recognizes human NMNAT2. Detects a band of ~35 kDa by Western blot. Not tested in other species.

Réactivité croisée (Details): Not tested in other species.

Attributs du produit: Polyclonal Antibody. Recognizes human NMNAT2. Detects a band of ~35 kDa by Western blot. Not tested in other species. Source: Guinea pig. Applications: ELISA, IHC, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. NMNAT2 catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form nicotinic acid mononucleotide (NaMN) as a substrate but with lower efficiency. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. Highly expressed in brain, in particular in cerebrum, cerebellum, occipital lobe, frontal lobe, temporal lobe and putamen. Also found in the heart, skeletal muscle, pancreas and islets of Langerhans. Has been shown to correlate with Alzheimer's disease in APPswe/PS1dE9 transgenic mice and delayed wallerian degeneration in cultured superior cervical ganglia (SCGs) from morphological changes, microtubule destruction and neurofilament degradation.

Stérilité: 0.2 μm filtered

Immunogène: Recombinant human NMNAT2.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Agent conservateur: Without preservative

Conseil sur la manipulation: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire:

+4°C

-20°C

Stable for at least 6 months after receipt when stored at -20°C.

Date de péremption: 6 months

Détails sur NMNAT2

Antigène: NMNAT2 (Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2))

Autre désignation: NMNAT2

Sujet:

Alternate Names/Synonyms: Nicotinamide Mononucleotide Adenylyltransferase 2, NMN Adenylyltransferase 2, NaMN Adenylyltransferase 2

Product Description: NMNAT2 catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form nicotinic acid mononucleotide (NaMN) as a substrate but with lower efficiency. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. Highly expressed in brain, in particular in cerebrum, cerebellum, occipital lobe, frontal lobe, temporal lobe and putamen. Also found in the heart, skeletal muscle, pancreas and islets of Langerhans. Has been shown to correlate with Alzheimer's disease in APPswe/PS1dE9 transgenic mice and delayed wallerian degeneration in cultured superior cervical ganglia (SCGs) from morphological changes, microtubule destruction and neurofilament degradation.

UniProt: Q9BZQ4