NMNAT2 anticorps

N° du produit ABIN1169224

Cet anticorps Souris Monoclonal détecte spécifiquement NMNAT2 dans ELISA, WB et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour NMNAT2 anticorps (ABIN1169224)

Antigène: NMNAT2 (Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NMNAT2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Clone: Nady-1

Détail du produit anti-NMNAT2 anticorps

Specificité: Recognizes human NMNAT2.

Réactivité croisée: Humain

Stérilité: 0.2 μm filtered

Immunogène: Recombinant human NMNAT2.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Détails sur NMNAT2

Antigène: NMNAT2 (Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2))

Autre désignation: NMNAT2

Sujet: NMNAT2 catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form nicotinic acid mononucleotide (NaMN) as a substrate but with lower efficiency. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. Highly expressed in brain, in particular in cerebrum, cerebellum, occipital lobe, frontal lobe, temporal lobe and putamen. Also found in the heart, skeletal muscle, pancreas and islets of Langerhans. Has been shown to correlate with Alzheimer's disease in APPswe/PS1dE9 transgenic mice and delayed wallerian degeneration in cultured superior cervical ganglia (SCGs) from morphological changes, microtubule destruction and neurofilament degradation.

UniProt: Q9BZQ4