DLL4 anticorps

N° du produit ABIN1169261

Il existe 1 publication pour ce produit. L’anticorps anti-DLL4 Monoclonal Rat est utilisé pour la détection de DLL4 dans des échantillons de Souris. Il a été validé pour FACS et ICC.

Aperçu rapide pour DLL4 anticorps (ABIN1169261)

Antigène: DLL4 (delta-Like 4 (DLL4))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp DLL4 est non-conjugé

Application: Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 9A1-5

Détail du produit anti-DLL4 anticorps

Specificité: Recognizes mouse DLL4.

Réactivité croisée: Souris

Purification: Purified from concentrated hybridoma tissue culture supernatant.

Pureté: >95 % (SDS-PAGE)

Immunogène: Recombinant mouse DLL4:Fc.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: In PBS containing 10 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Références pour anticorps anti-DLL4 (ABIN1169261)

Fiorini, Ferrero, Merck, Favre, Pierres, Luther, MacDonald: "Cutting edge: thymic crosstalk regulates delta-like 4 expression on cortical epithelial cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 12, pp. 8199-203, (2008) (PubMed).

Détails sur DLL4

Antigène: DLL4 (delta-Like 4 (DLL4))

Autre désignation: DLL4

Sujet: The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, promoting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.

UniProt: Q9JI71

Pathways: Signalisation Notch