PIDD anticorps
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- Antigène Voir toutes PIDD Anticorps
- PIDD (P53-Induced Death Domain Protein (PIDD))
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Reactivité
- Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp PIDD est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- Recognizes mouse PIDD.
- Réactivité croisée
- Souris
- Purification
- Purified from concentrated hybridoma tissue culture supernatant.
- Pureté
- >95 % (SDS-PAGE)
- Immunogène
- Mouse PIDD (Death Domain).
- Clone
- Lise-1
- Isotype
- IgG2b
- Top Product
- Discover our top product PIDD Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - Date de péremption
- 12 months
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- Antigène
- PIDD (P53-Induced Death Domain Protein (PIDD))
- Autre désignation
- PIDD (PIDD Produits)
- Synonymes
- anticorps 1200011D09Rik, anticorps AU042446, anticorps Pidd, anticorps LRDD, anticorps Lrdd, anticorps p53 induced death domain protein 1, anticorps p53-induced death domain protein 1, anticorps Pidd1, anticorps PIDD1
- Sujet
- PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways.
- UniProt
- Q9ERV7
- Pathways
- Signalisation p53, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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