Caspase 1 p20 anticorps (Biotin)

N° du produit ABIN1169382

Cet anticorps anti-Caspase 1 p20 Monoclonal Souris conjugué à Biotin (Clone Bally-1) (ABIN1169382) détecte spécifiquement Caspase 1 p20 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Caspase 1 p20 anticorps (Biotin) (ABIN1169382)

Antigène: Caspase 1 p20

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Caspase 1 p20 est conjugé à/à la Biotin

Application: Western Blotting (WB)

Clone: Bally-1

Détail du produit anti-Caspase 1 p20 anticorps (Biotin)

Fonction: anti-Caspase-1 (p20) (human), mAb (Bally-1) (Biotin)

Specificité: Recognizes endogenous full-length and activated (p20 fragment) human caspase-1.

Attributs du produit: Monoclonal Antibody. Recognizes endogenous full-length and activated (p20 fragment) human caspase-1. Isotype: Mouse IgG1. Clone: Bally-1. Applications: WB. Liquid. In PBS containing 0.02 % sodium azide. Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals.

Purification: Purified from concentrated hybridoma tissue culture supernatant.

Pureté: >95 % (SDS-PAGE)

Immunogène: Recombinant human caspase-1.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: In PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Détails sur Caspase 1 p20

Antigène: Caspase 1 p20

Autre désignation: Caspase-1 p20

Sujet:

Alternate Names/Synonyms: Interleukin-1 beta Convertase, IL-1BC, Interleukin-1 beta-converting Enzyme, ICE

Product Description: Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals.

UniProt: P29466