Caspase 1 p20 anticorps (Biotin)

N° du produit ABIN1169383

Cet anticorps Souris Monoclonal détecte spécifiquement Caspase 1 p20 dans WB, IP et IHC. Il présente une réactivité envers Souris et a été mentionné dans 1 publication.

Aperçu rapide pour Caspase 1 p20 anticorps (Biotin) (ABIN1169383)

Antigène: Caspase 1 p20

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Caspase 1 p20 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)

Clone: Casper-1

Détail du produit anti-Caspase 1 p20 anticorps (Biotin)

Specificité: Recognizes endogenous full-length and activated (p20 fragment) mouse caspase-1.

Réactivité croisée: Souris

Purification: Purified from concentrated hybridoma tissue culture supernatant.

Pureté: >95 % (SDS-PAGE)

Immunogène: Recombinant mouse caspase-1.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: In PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Références pour anticorps anti-Caspase 1 p20 (Biotin) (ABIN1169383)

Carpentier, Ni, Duggan, James, Cookson, Hamerman: "The signaling adaptor BCAP inhibits NLRP3 and NLRC4 inflammasome activation in macrophages through interactions with Flightless-1." dans: Science signaling, Vol. 12, Issue 581, (2020) (PubMed).

Détails sur Caspase 1 p20

Antigène: Caspase 1 p20

Autre désignation: Caspase-1 p20

Sujet: Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals.

UniProt: P29452