JAG1 anticorps (FITC)
Aperçu rapide pour JAG1 anticorps (FITC) (ABIN1169437)
Antigène
Voir toutes JAG1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- anti-Jagged-1 (human), mAb (J1G53-3) (FITC)
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Specificité
- Recognizes human Jagged-1. Detects a band of ~180 kDa by Western blot.
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Attributs du produit
- Monoclonal Antibody. Recognizes human Jagged-1. Detects a band of ~180 kDa by Western blot. Isotype: Mouse IgG1kappa. Clone: J1G53-3. Applications: FACS. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).
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Stérilité
- 0.2 μm filtered
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Immunogène
- Recombinant human Jagged-1.
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Isotype
- IgG1 kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 0.2μm-filtered solution in PBS, pH 7.4.
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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+4°C
-20°C
Stable for at least 1 year after receipt when stored at -20°C.
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Date de péremption
- 12 months
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- JAG1 (Jagged 1 (JAG1))
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Autre désignation
- Jagged-1
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Sujet
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Alternate Names/Synonyms: Protein Jagged-1, CD339, JAG1
Product Description: Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).
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UniProt
- P78504
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Pathways
- Signalisation Notch, Stem Cell Maintenance
Antigène
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