ACE2 anticorps

N° du produit ABIN1169449

Cet anticorps Souris Monoclonal détecte spécifiquement ACE2 dans WB, ELISA et FACS. Il présente une réactivité envers Humain et a été mentionné dans 4+ publications.

Aperçu rapide pour ACE2 anticorps (ABIN1169449)

Antigène: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ACE2 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Clone: AC18F

Détail du produit anti-ACE2 anticorps

Specificité: Recognizes human ACE2.

Réactivité croisée: Humain

Stérilité: 0.2 μm filtered

Immunogène: Recombinant human ACE2.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Références pour anticorps anti-ACE2 (ABIN1169449)

Chaouat, Achdout, Kol, Berhani, Roi, Vitner, Melamed, Politi, Zahavy, Brizic, Lenac Rovis, Alfi, Wolf, Jonjic, Israely, Mandelboim: "SARS-CoV-2 receptor binding domain fusion protein efficiently neutralizes virus infection." dans: PLoS pathogens, Vol. 17, Issue 12, pp. e1010175, (2022) (PubMed).

Chaouat, Brizic, Kucan Brlic, Atari, Kliker, Alfi, Mandelboim, Wolf, Tafish, Kol, Jonjic, Mandelboim: "Anti-human ACE2 antibody neutralizes and inhibits virus production of SARS-CoV-2 variants of concern." dans: iScience, Vol. 25, Issue 9, pp. 104935, (2022) (PubMed).

Buchrieser, Dufloo, Hubert, Monel, Planas, Rajah, Planchais, Porrot, Guivel-Benhassine, Van der Werf, Casartelli, Mouquet, Bruel, Schwartz: "Syncytia formation by SARS-CoV-2-infected cells." dans: The EMBO journal, pp. e106267, (2020) (PubMed).

Zulli, Rai, Buxton, Burrell, Hare: "Co-localization of angiotensin-converting enzyme 2-, octomer-4- and CD34-positive cells in rabbit atherosclerotic plaques." dans: Experimental physiology, Vol. 93, Issue 5, pp. 564-9, (2008) (PubMed).

Détails sur ACE2

Antigène: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Autre désignation: ACE2

Sujet: ACE2 has direct effects on cardiac functions. It is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE2 converts angiotensin I to angiotensin 1-9. ACE2 was also identified as a functional receptor for SARS coronavirus.

UniProt: Q9BYF1

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour