POLM anticorps (AA 6-18)

N° du produit ABIN117919

Cet anticorps Lapin Polyclonal détecte spécifiquement POLM dans WB et EIA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour POLM anticorps (AA 6-18) (ABIN117919)

Antigène: POLM (Polymerase (DNA Directed), mu (POLM))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLM est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-POLM anticorps

Épitope: AA 6-18

Séquence: Peptide sequence: R-R-A-R-V-G-S-P-S-G-D-A-A-C

Specificité: This is an affinity purified antibody produced by Immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.

Purification: Immunoaffinity chromatography.

Immunogène: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to aa 6-18 of Human POLM µ (DNA polymerase mu). POLM µ is a template-directed terminal deoxynucleotidetransferase that shows a preferential expression in proliferating lymphoid cells.

Information d'application

Indications d'application: This affinity purified antibody has been tested for use in ELISA against the immunizingpeptide. Reactivity in other immunoassays is unknown. This product has been assayed byELISA against 0.1 μg of the immunizing peptide. A 1: 33,000 to 1: 135,000 dilution of the antibody is recommended for this assay.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 2.1 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Dilute only prior to immediate use. Avoid cycles of freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store vial at -20 °C prior to opening. Aliquot contents and freeze at -20 °C or below for extended storage. Centrifuge product if not completely clear after standing at room temperature. This product is stable for one month at 2-8 °C as an undiluted liquid.

Détails sur POLM

Antigène: POLM (Polymerase (DNA Directed), mu (POLM))

Autre désignation: DNA Polymerase mu

Sujet: DNA ploymerase mu is a template directed terminal deoxynucleotidetransferase that shows a preferential expression in proliferating lymphoid cells. It seems to act as an Ig mutase which is responsible for immunoglobulin (Ig) gene hypermutation.Synonyms: POLM, Pol Mu, Tdt-N, TdtN

ID gène: 27434

NCBI Accession: NP_037416

UniProt: Q9NP87

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response