RNF2 anticorps (AA 189-201)
Aperçu rapide pour RNF2 anticorps (AA 189-201) (ABIN117940)
Antigène
Voir toutes RNF2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 189-201
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Séquence
- 1 msqavqtngt qplsktwels lyelqrtpqe aitdgleivv sprslhselm cpicldmlkn 61 tmttkeclhr fcadciital rsgnkecptc rkklvskrsl rpdpnfdali skiypsrdey 121 eahqervlar inkhnnqqal shsieeglki qamnrlqrgk kqqiengsga edngdsshcs 181 nasthsnqea gpsnkrtkts ddsgleldnn naamaidpvm dgaseielvf rphptlmekd 241 dsaqtryikt sgnatvdhls kylavrlale elrskgesnq mnldtasekq ytiyiatasg 301 qftvlngsfs lelvsekywk vnkpmelyya ptkehk
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Specificité
- This antibody detects RING1B.
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Réactivité croisée (Details)
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Species reactivity (expected):Zebrafish.
Species reactivity (tested):Human, Chimpanzee, Orangutan, Mouse, Rrat, Dog, Bovine, Frog and Chicken. -
Purification
- Immunoaffinity Chromatography.
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Immunogène
- Synthetic peptide corresponding aa 189-201 of Human RING1B protein
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Indications d'application
- ELISA: 1/5,000-1/25,000. Western blot: 1/500-1/2,000. Expect a band approximately 38 kDa in size corresponding toRING1B by in the appropriate cell lysate or extract. Immunofluorescence.
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Restrictions
- For Research Use only
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Concentration
- 1.2 mg/mL (by UV absorbance at 280 nm)
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Buffer
- 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2 as buffer and 0.01 % (w/v) Sodium Azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store undiluted at 2-8 °C. DO NOT FREEZE!
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- RNF2 (Ring Finger Protein 2 (RNF2))
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Autre désignation
- RNF2
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Sujet
- RING1B (also known as BAP1, DING, Polycomb-M33 interacting protein Ring1B, Ring finger protein 1b, Ring finger protein 2 and RNF2) is one of the PcG proteins. The polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), a ubiquitin-conjugating enzyme that possesses ubiquitin ligase activity.Synonyms: BAP-1, BAP1, DING, E3 ubiquitin-protein ligase RING2, HIP2-interacting protein 3, HIPI3, Protein DinG, RING finger protein 2, RING1B
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ID gène
- 6045
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NCBI Accession
- NP_009143
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UniProt
- Q99496
Antigène
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