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CTLA4 anticorps (PE)

L’anticorps Souris Monoclonal anti-CTLA4 a été validé pour FACS. Il convient pour détecter CTLA4 dans des échantillons de Humain.
N° du produit ABIN118892

Aperçu rapide pour CTLA4 anticorps (PE) (ABIN118892)

Antigène

Voir toutes CTLA4 Anticorps
CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Reactivité

  • 176
  • 112
  • 51
  • 14
  • 10
Humain

Hôte

  • 100
  • 92
  • 24
  • 22
  • 9
  • 2
  • 1
  • 1
  • 1
Souris

Clonalité

  • 181
  • 67
  • 3
Monoclonal

Conjugué

  • 118
  • 20
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  • 15
  • 7
  • 5
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  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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Cet anticorp CTLA4 est conjugé à/à la PE

Application

  • 101
  • 83
  • 65
  • 43
  • 30
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  • 13
  • 10
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Flow Cytometry (FACS)

Clone

BNI3
  • Specificité

    This antibody recognises the CD152 cell surface antigen, also known as CTLA-4 (cytotoxic T-lymphocyteassociated antigen 4).

    Purification

    Affinity Chromatography

    Immunogène

    Human CTLA-4/human IgG heavy chain fusion protein. Spleen cells from immunised BALB/c mice were fused with cells of the mouse P3/X63-Ag8.653 myeloma cell line.

    Isotype

    IgG2a
  • Indications d'application

    Flow Cytometry: Use 20 μL of neat antibody to label 5x10e5 cells in 100 μL. Membrane permeabilisation is required for this application.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Buffer

    PBS containing 0.09 % Sodium Azide as preservative and 0.2 % BSA as stabilizer.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Dilute only prior to immediate use

    Stock

    4 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! Freezing alkaline phosphatase conjugates will result in a substantial loss of enzymatic activity.
  • Antigène

    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

    Autre désignation

    CD152 / CTLA4

    Sujet

    CD152 is a 45kD glycoprotein, expressed normally as a disulphide-linked homodimer. It is expressed transiently on the surface of T cells following activation (peaking at 3 days), but is often present within the cytoplasm. CD152 is a ligand for CD80 and CD86, and is important in cellular interactions during the immune response.Synonyms: CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4

    ID gène

    1493

    NCBI Accession

    NP_001032720

    UniProt

    P16410

    Pathways

    Cancer Immune Checkpoints
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