HLA B7 anticorps (FITC)

N° du produit ABIN118933

Cet anticorps Souris Monoclonal détecte spécifiquement HLA B7 dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour HLA B7 anticorps (FITC) (ABIN118933)

Antigène: HLA B7 (HLA Class I B7 Alpha (HLA B7))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HLA B7 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Clone: BB7-1

Détail du produit anti-HLA B7 anticorps (FITC)

Specificité: This antibody recognises the Human HLA-B7 antigen and does not cross-react with HLA-B27 or other related HLA antigens. It can be used to distinguish true HLA-B27 positives from false HLA-B27 positives (i.e. HLA-B7 positive) in the investigation of such diseases as ankylosing spondylitis and anterior uveitis.

Réactivité croisée (Details): Species reactivity (expected):Cynomolgus monkey.
Species reactivity (tested):Human.

Purification: Affinity Chromatography on Protein G

Immunogène: Papain solubilized HLA-B7 antigen.

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: use 10 μL of neat - 1/10 diluted antibody to label 1x10^6 cells in 100 μL whole blood.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide, 1 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur HLA B7

Antigène: HLA B7 (HLA Class I B7 Alpha (HLA B7))

Sujet: HLA B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa. Hundreds of HLA B alleles have been described. The HLA B gene is part of the human HLA complex on chromosome 6 and there are a large number of variant alleles of this gene.Synonyms: B-7 alpha chain, HLA class I histocompatibility antigen, HLAB, MHC class I antigen B7

ID gène: 3106

NCBI Accession: NP_005505

UniProt: P01889

Pathways: Human Leukocyte Antigen (HLA) in Adaptive Immune Response