HLA B7 anticorps

N° du produit ABIN118934

L’anticorps anti-HLA B7 Monoclonal Souris est utilisé pour la détection de HLA B7 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour HLA B7 anticorps (ABIN118934)

Antigène: HLA B7 (HLA Class I B7 Alpha (HLA B7))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HLA B7 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: BB7-1

Détail du produit anti-HLA B7 anticorps

Specificité: This antibody recognises the HLA-B7 antigen and does not cross-react with HLA-B27 or other related antigens. It can be used to distinguish true HLA-B27 positives from false HLA-B27 positives (i.e. HLA-B7 positive) in the investigation of diseases such as ankylosing spondylitis and anterior uveitis.

Purification: Affinity Chromatography on Protein A.

Immunogène: Papain solubilized HLA-B7 antigen.

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry: 1/50, Use 10 μL of the suggested working dilution to label 1 x 10^6 cells or 100 μL whole blood.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur HLA B7

Antigène: HLA B7 (HLA Class I B7 Alpha (HLA B7))

Sujet: HLA B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa. Hundreds of HLA B alleles have been described. Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). This antibody can be used for HLA typing.Synonyms: B-7 alpha chain, HLA class I histocompatibility antigen, HLAB, MHC class I antigen B7

ID gène: 3106

NCBI Accession: NP_005505

UniProt: P01889

Pathways: Human Leukocyte Antigen (HLA) in Adaptive Immune Response