HLA B7 anticorps (PE)
Aperçu rapide pour HLA B7 anticorps (PE) (ABIN118935)
Antigène
Voir toutes HLA B7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody binds to the HLA-B7 antigen and does not cross-react with HLA-B27 or other related HLA antigens. It can be used to distinguish true HLA-B27 positives from false HLA-B27 positives (i.e. HLA-B7 positive) in the investigation of such diseases as ankylosing spondylitis and anterior uveitis.
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Purification
- Affinity chromatography on Protein G
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Immunogène
- Papain solubilized HLA-B7 antigen.
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Isotype
- IgG1
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Indications d'application
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Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Reconstitution
- Restore with 1 mL distilled water.
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Buffer
- PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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Stockage commentaire
- On receipt store the antibody (in aliquots) at -20 °C.
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- HLA B7 (HLA Class I B7 Alpha (HLA B7))
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Sujet
- HLA B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa. Hundreds of HLA B alleles have been described.Synonyms: B-7 alpha chain, HLA class I histocompatibility antigen, HLAB, MHC class I antigen B7
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ID gène
- 3106
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NCBI Accession
- NP_005505
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UniProt
- P01889
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Pathways
- Human Leukocyte Antigen (HLA) in Adaptive Immune Response
Antigène
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