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CD147 anticorps

L’anticorps Souris Monoclonal anti-CD147 a été validé pour WB, FACS, IF et IP. Il convient pour détecter CD147 dans des échantillons de Humain. Il y a 1 publication disponible.
N° du produit ABIN119252

Aperçu rapide pour CD147 anticorps (ABIN119252)

Antigène

Voir toutes CD147 (BSG) Anticorps
CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Reactivité

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Humain

Hôte

  • 125
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Souris

Clonalité

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Monoclonal

Conjugué

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Cet anticorp CD147 est non-conjugé

Application

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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone

MEM-M6-1
  • Specificité

    This antibody recognizes the Human CD147 cell surface antigen, a 50-60 kDa glycoprotein also known as neurothelin and basigin.

    Réactivité croisée (Details)

    Species reactivity (tested):Human.

    Purification

    Affinity Chromatography on Protein A

    Immunogène

    CD147Rg, consisting of the cDNA coding for the hinge region, CH2 and CH3 domains of Human IgG1.

    Isotype

    IgG1
  • Indications d'application

    Flow cytometry: 1/10 - 1/50, use 10 μL of the suggested working dilution to label 106 cells. Immunoprecipitation. Western Blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    PBS, pH 7.4 without preservatives, None

    Agent conservateur

    Without preservative

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • Schneiderhan, Scheler, Holzmann, Marx, Gschwend, Bucholz, Gress, Seufferlein, Adler, Oswald: "CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models." dans: Gut, Vol. 58, Issue 10, pp. 1391-8, (2009) (PubMed).

  • Antigène

    CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

    Autre désignation

    CD147

    Sujet

    CD147 is a 50-60kD glycoprotein also known as neurothelin and basigin. CD147 is broadly expressed on peripheral blood cells and by endothelial cells. Expression upon T cells is increased following activation.Synonyms: 5F7, BSG, Basigin, Collagenase stimulatory factor, EMMPRIN, Extracellular matrix metalloproteinase inducer, Leukocyte activation antigen M6, OK blood group antigen, TCSF, Tumor cell-derived collagenase stimulatory factor

    ID gène

    682

    NCBI Accession

    NP_001719

    UniProt

    P35613

    Pathways

    S100 Proteins
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