MHC Class I RT1.Aa alpha-Chain (RT1.AA) anticorps

N° du produit ABIN120149

L’anticorps anti-MHC Class I RT1.Aa alpha-Chain Monoclonal Souris est utilisé pour la détection de MHC Class I RT1.Aa alpha-Chain dans des échantillons de Rat. Il a été validé pour FACS et IHC (fro).

Aperçu rapide pour MHC Class I RT1.Aa alpha-Chain (RT1.AA) anticorps (ABIN120149)

Antigène: MHC Class I RT1.Aa alpha-Chain (RT1.AA)

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: F16-4-4

Détail du produit

Purification: Affinity chromatography on Protein G

Immunogène: Partially purified rat MHC antigens. Spleen cells of immunised BALB/c mice were fused with cells from the NS-1 mouse myeloma line.

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry (1/100-1/200). Immunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détail du antigène

Antigène: MHC Class I RT1.Aa alpha-Chain (RT1.AA)

Autre désignation: MHC Class I (RT1Aa)

Sujet: MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44 kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.Synonyms: RT1 class I histocompatibility antigen AA alpha chain

ID gène: 10116

UniProt: P16391