Integrin beta 3 anticorps

N° du produit ABIN120250

Cet anticorps Hamster Monoclonal détecte spécifiquement Integrin beta 3 dans FACS et IP. Il présente une réactivité avec des échantillons de Souris et Rat.

Aperçu rapide pour Integrin beta 3 anticorps (ABIN120250)

Antigène: Integrin beta 3 (ITGB3)

Reactivité: Souris, Rat

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin beta 3 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: HM beta 3-1

Détail du produit anti-Integrin beta 3 anticorps

Purification: Affinity Chromatography on Protein G.

Immunogène: Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4. Spleen cells from immunised Armenian hamsters were fused with cells of the P3U1 mouse myeloma cell line.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry: Use 10 μL of 1/10-1/25 diluted antibody to label 10^6 cells in 100 μL. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Integrin beta 3

Antigène: Integrin beta 3 (ITGB3)

Autre désignation: CD61 / ITGB3

Sujet: CD61 is a 90kD a type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptor for a variety of ligands including fibrinogen, fibronectin, von Willebrands factor (vWF), vitronectin and thrombospondin.Synonyms: GP3A, GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa

ID gène: 10090

UniProt: O54890

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex