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CD31 anticorps

PECAM1 Reactivité: Rat FACS, WB, IHC (fro), EIA Hôte: Souris Monoclonal TLD-3A12 unconjugated
N° du produit ABIN120452
  • Antigène Voir toutes CD31 (PECAM1) Anticorps
    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
    Reactivité
    • 275
    • 142
    • 71
    • 59
    • 42
    • 28
    • 22
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    • 7
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    • 2
    • 1
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    Rat
    Hôte
    • 158
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    • 48
    • 7
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    Souris
    Clonalité
    • 232
    • 133
    • 1
    Monoclonal
    Conjugué
    • 156
    • 33
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    • 2
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    • 1
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    • 1
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    • 1
    Cet anticorp CD31 est non-conjugé
    Application
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    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody recognises PECAM-1 (CD31). Clone TLD-3A12 has been shown to partially block the proliferative response of antigen-specific CD4+ T cells to antigen-presenting cells and relevant antigen.
    Purification
    Affinity Chromatography on Protein G
    niveau d'endotoxine
    Low Endotoxin
    Immunogène
    Activated, Lewis Rat derived microglial cells. Remarks: Spleen cells from immunised BALB/c mouse were fused with cells of the mouse SP2 myeloma cell line.
    Clone
    TLD-3A12
    Isotype
    IgG1
    Top Product
    Discover our top product PECAM1 Anticorps primaire
  • Indications d'application
    ELISA. Western Blot. Flow Cytometry: 1/50 - 1/100, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunohistochemistry on frozen sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Endotoxin Level: less than 0.01 EU/ug
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS without preservatives or stabilizers
    Agent conservateur
    Without preservative
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • Antigène
    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
    Autre désignation
    CD31 / PECAM1 (PECAM1 Produits)
    Synonymes
    anticorps CD31, anticorps CD31/EndoCAM, anticorps GPIIA', anticorps PECA1, anticorps PECAM-1, anticorps endoCAM, anticorps C85791, anticorps Cd31, anticorps Pecam, anticorps platelet/endothelial cell adhesion molecule 1, anticorps platelet and endothelial cell adhesion molecule 1, anticorps pecam1, anticorps PECAM1, anticorps Pecam1
    Sujet
    CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed on the surface of endothelial cells, and concentrated at the junction between them. It is also weakly expressed on many peripheral lymphoid cells and platelets. CD31 has been used to measure angiogenesis in association with tumor recurrence. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas). CD31 is a type 1 transmembrane protein expressed primarily on endothelial cells, platelets and leucocytes.Synonyms: End °CAM, GPIIA', PECAM-1, Platelet endothelial cell adhesion molecule
    ID gène
    29583
    NCBI Accession
    NP_113779
    UniProt
    Q3SWT0
    Pathways
    Regulation of Actin Filament Polymerization
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